Publication: SCD5 Regulation by VHL Affects Cell Proliferation and Lipid Homeostasis in ccRCC
SCD5 Regulation by VHL Affects Cell Proliferation and Lipid Homeostasis in ccRCC
Date
Date
Date
Citations
Ganner, A., Philipp, A., Lagies, S., Wingendorf, L., Wang, L., Pilz, F., Welte, T., Grand, K., Lienkamp, S. S., Klein, M., Kammerer, B., Frew, I. J., Walz, G., & Neumann-Haefelin, E. (2023). SCD5 Regulation by VHL Affects Cell Proliferation and Lipid Homeostasis in ccRCC. Cells, 12(6), 835. https://doi.org/10.3390/cells12060835
Abstract
Abstract
Abstract
Clear cell renal cell carcinoma (ccRCC) is the most common histological subtype of renal cancer, and inactivation of the VHL tumor suppressor gene is found in almost all cases of hereditary and sporadic ccRCCs. CcRCC is associated with the reprogramming of fatty acid metabolism, and stearoyl-CoA desaturases (SCDs) are the main enzymes controlling fatty acid composition in cells. In this study, we report that mRNA and protein expression of the stearoyl-CoA desaturase SCD5 is downregulated in VHL-deficient cell lines. Similarly, in C. e
Metrics
Downloads
Views
Additional indexing
Creators (Authors)
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Item Type
Item Type
Item Type
In collections
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Free Access at
Free Access at
Free Access at
Publisher DOI
Metrics
Downloads
Views
Citations
Ganner, A., Philipp, A., Lagies, S., Wingendorf, L., Wang, L., Pilz, F., Welte, T., Grand, K., Lienkamp, S. S., Klein, M., Kammerer, B., Frew, I. J., Walz, G., & Neumann-Haefelin, E. (2023). SCD5 Regulation by VHL Affects Cell Proliferation and Lipid Homeostasis in ccRCC. Cells, 12(6), 835. https://doi.org/10.3390/cells12060835
