Publication: Host Factor Requirements of the Rotavirus Viroplasm
Host Factor Requirements of the Rotavirus Viroplasm
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Vetter, J. (2024). Host Factor Requirements of the Rotavirus Viroplasm. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-258704
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Rotavirus (RV) is the primary etiological agent responsible for severe gastroenteritis and dehydration worldwide in infants and young animals. RV virions are icosahedral, non-enveloped particles with three concentric layers of protein (TLP, triple-layered particle). The inner layer is termed core or single-layered particle (SLP) and is composed of the core-shell protein VP2 that holds underneath each five-fold axis one copy of both the RNA-dependent RNA polymerase (RdRp) VP1 and the guanylylmethyltransferase VP3. Each core encapsidate
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Vetter, J. (2024). Host Factor Requirements of the Rotavirus Viroplasm. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-258704
