Publication: Advancing animal tuberculosis surveillance using culture-independent long-read whole-genome sequencing
Advancing animal tuberculosis surveillance using culture-independent long-read whole-genome sequencing
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Ghielmetti, G., Loubser, J., Kerr, T. J., Stuber, T., Thacker, T., Martin, L. C., O’Hare, M. A., Mhlophe, S. K., Okunola, A., Loxton, A. G., Warren, R. M., Moseley, M. H., Miller, M. A., & Goosen, W. J. (2023). Advancing animal tuberculosis surveillance using culture-independent long-read whole-genome sequencing. Frontiers in Microbiology, 14, 1307440. https://doi.org/10.3389/fmicb.2023.1307440
Abstract
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Abstract
Animal tuberculosis is a significant infectious disease affecting both livestock and wildlife populations worldwide. Effective disease surveillance and characterization of Mycobacterium bovis (M. bovis) strains are essential for understanding transmission dynamics and implementing control measures. Currently, sequencing of genomic information has relied on culture-based methods, which are time-consuming, resource-demanding, and concerning in terms of biosafety. This study explores the use of culture-independent long-read whole-genome
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Creators (Authors)
- Loubser, Johannes
- Kerr, Tanya J
- Stuber, Tod
- Thacker, Tyler
- Martin, Lauren C
- O'Hare, Michaela A
- Mhlophe, Sinegugu K
- Okunola, Abisola
- Loxton, Andre G
- Warren, Robin M
- Moseley, Mark H
- Miller, Michele A
- Goosen, Wynand J
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Ghielmetti, G., Loubser, J., Kerr, T. J., Stuber, T., Thacker, T., Martin, L. C., O’Hare, M. A., Mhlophe, S. K., Okunola, A., Loxton, A. G., Warren, R. M., Moseley, M. H., Miller, M. A., & Goosen, W. J. (2023). Advancing animal tuberculosis surveillance using culture-independent long-read whole-genome sequencing. Frontiers in Microbiology, 14, 1307440. https://doi.org/10.3389/fmicb.2023.1307440
