Publication: An R-based reproducible and user-friendly preprocessing pipeline for CyTOF data
An R-based reproducible and user-friendly preprocessing pipeline for CyTOF data
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Crowell, H. L., Chevrier, S., Jacobs, A., Sivapatham, S., Bodenmiller, B., Robinson, M. D., et al, & Kölzer, V. (2020). An R-based reproducible and user-friendly preprocessing pipeline for CyTOF data. F1000Research, 9, 1263. https://doi.org/10.12688/f1000research.26073.2
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Mass cytometry (CyTOF) has become a method of choice for in-depth characterization of tissue heterogeneity in health and disease, and is currently implemented in multiple clinical trials, where higher quality standards must be met. Currently, preprocessing of raw files is commonly performed in independent standalone tools, which makes it difficult to reproduce. Here, we present an R pipeline based on an updated version of CATALYST that covers all preprocessing steps required for downstream mass cytometry analysis in a fully reproducib
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- Crowell, Helena L
- Chevrier, Stéphane
- Jacobs, Andrea
- Sivapatham, Sujana
- Bodenmiller, Bernd
- Robinson, Mark D
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Crowell, H. L., Chevrier, S., Jacobs, A., Sivapatham, S., Bodenmiller, B., Robinson, M. D., et al, & Kölzer, V. (2020). An R-based reproducible and user-friendly preprocessing pipeline for CyTOF data. F1000Research, 9, 1263. https://doi.org/10.12688/f1000research.26073.2
