Publication: Luminal signalling links cell communication to tissue architecture during organogenesis
Luminal signalling links cell communication to tissue architecture during organogenesis
Date
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Citations
Durdu, S., Iskar, M., Revenu, C., Schieber, N., Kunze, A., Bork, P., Schwab, Y., & Gilmour, D. (2014). Luminal signalling links cell communication to tissue architecture during organogenesis. Nature, 515(7525), 120–124. https://doi.org/10.1038/nature13852
Abstract
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Morphogenesis is the process whereby cell collectives are shaped into differentiated tissues and organs. The self-organizing nature of morphogenesis has been recently demonstrated by studies showing that stem cells in three-dimensional culture can generate complex organoids, such as mini-guts, optic-cups and even mini-brains. To achieve this, cell collectives must regulate the activity of secreted signalling molecules that control cell differentiation, presumably through the self-assembly of microenvironments or niches. However, mecha
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Creators (Authors)
- Durdu, Sevi
- Iskar, Murat
- Revenu, Celine
- Schieber, Nicole
- Kunze, Andreas
- Bork, Peer
- Schwab, Yannick
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Citations
Durdu, S., Iskar, M., Revenu, C., Schieber, N., Kunze, A., Bork, P., Schwab, Y., & Gilmour, D. (2014). Luminal signalling links cell communication to tissue architecture during organogenesis. Nature, 515(7525), 120–124. https://doi.org/10.1038/nature13852
