Publication: Investigating the pathophysiological BOLD fMRI response to hypercapnia in patients with steno-occlusive disease
Investigating the pathophysiological BOLD fMRI response to hypercapnia in patients with steno-occlusive disease
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van Niftrik, C. H. B. (2020). Investigating the pathophysiological BOLD fMRI response to hypercapnia in patients with steno-occlusive disease. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-197035
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The blood oxygenation-level dependent (BOLD) functional magnetic resonance imaging (fMRI) signal constitutes a complex interplay between different neurophysiological parameters, primarily cerebral blood flow (CBF) and cerebral metabolic rate of oxygen (CMRO2). This represents a major drawback of BOLD fMRI, while the unknown extent of this interplay limits its clinical applicability. For instance, the BOLD fMRI response to hypercapnia is used to measure cerebrovascular reactivity (CVR). CVR is a measurement of the change in CBF in resp
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van Niftrik, C. H. B. (2020). Investigating the pathophysiological BOLD fMRI response to hypercapnia in patients with steno-occlusive disease. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-197035
