Publication: Donation type and the effect of pre-transplant donor specific antibodies – Data from the Swiss Transplant Cohort Study
Donation type and the effect of pre-transplant donor specific antibodies – Data from the Swiss Transplant Cohort Study
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de Rougemont, O., Deng, Y., Frischknecht, L., Wehmeier, C., Villard, J., Ferrari-Lacraz, S., Golshayan, D., Gannage, M., Binet, I., Wirthmueller, U., Sidler, D., Schachtner, T., Schaub, S., & Nilsson, J. (2023). Donation type and the effect of pre-transplant donor specific antibodies – Data from the Swiss Transplant Cohort Study. Frontiers in Immunology, 14, 1104371. https://doi.org/10.3389/fimmu.2023.1104371
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Introduction The type of donation may affect how susceptible a donor kidney is to injury from pre-existing alloimmunity. Many centers are, therefore, reluctant to perform donor specific antibody (DSA) positive transplantations in the setting of donation after circulatory death (DCD). There are, however, no large studies comparing the impact of pre-transplant DSA stratified on donation type in a cohort with a complete virtual cross-match and long-term follow-up of transplant outcome.
Methods We investigated the effect of pre-transplan
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de Rougemont, O., Deng, Y., Frischknecht, L., Wehmeier, C., Villard, J., Ferrari-Lacraz, S., Golshayan, D., Gannage, M., Binet, I., Wirthmueller, U., Sidler, D., Schachtner, T., Schaub, S., & Nilsson, J. (2023). Donation type and the effect of pre-transplant donor specific antibodies – Data from the Swiss Transplant Cohort Study. Frontiers in Immunology, 14, 1104371. https://doi.org/10.3389/fimmu.2023.1104371