Publication: The Effect of Hydroxyethyl Starches (HES 130/0.42 and HES 200/0.5) on Activated Renal Tubular Epithelial Cells
The Effect of Hydroxyethyl Starches (HES 130/0.42 and HES 200/0.5) on Activated Renal Tubular Epithelial Cells
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Wittlinger, M., Schläpfer, M., De Conno, E., Roth Z’graggen, B., Reyes, L., Booy, C., Schimmer, R. C., Seifert, B., Burmeister, M. A., Spahn, D. R., & Beck-Schimmer, B. (2010). The Effect of Hydroxyethyl Starches (HES 130/0.42 and HES 200/0.5) on Activated Renal Tubular Epithelial Cells. Anesthesia and Analgesia, 110(2), 531–540. https://doi.org/10.1213/ANE.0b013e3181c03c97
Abstract
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Background: Acute renal failure is a frequent complication of sepsis. Hydroxyethyl starch (HES) is widely used in the treatment of such patients. However, the effect of HES on renal function during sepsis remains controversial. We established an in vitro model of tumor necrosis factor-alpha (TNF-alpha)-stimulated human proximal tubular epithelial (HK-2) cells to assess the possible effects of HES 130/0.42 and HES 200/0.5 on these activated cells. Methods: HK-2 cells were stimulated with TNF-alpha in the presence or absence of HES 130/
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- Wittlinger, M
- Schläpfer, M
- De Conno, E
- Roth Z'graggen, B
- Reyes, L
- Booy, C
- Seifert, B
- Burmeister, M A
- Spahn, D R
- Beck-Schimmer, B
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Wittlinger, M., Schläpfer, M., De Conno, E., Roth Z’graggen, B., Reyes, L., Booy, C., Schimmer, R. C., Seifert, B., Burmeister, M. A., Spahn, D. R., & Beck-Schimmer, B. (2010). The Effect of Hydroxyethyl Starches (HES 130/0.42 and HES 200/0.5) on Activated Renal Tubular Epithelial Cells. Anesthesia and Analgesia, 110(2), 531–540. https://doi.org/10.1213/ANE.0b013e3181c03c97
