Publication: The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance
The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance
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Vannini, N., Campos, V., Girotra, M., Trachsel, V., Rojas-Sutterlin, S., Tratwal, J., Ragusa, S., Stefanidis, E., Ryu, D., Rainer, P. Y., Nikitin, G., Giger, S., Li, T. Y., Semilietof, A., Oggier, A., Yersin, Y., Tauzin, L., Pirinen, E., Cheng, W.-C., … Duchosal, M. A. (2019). The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance. Cell Stem Cell, 24(3), 405-418.e7. https://doi.org/10.1016/j.stem.2019.02.012
Abstract
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Abstract
It has been recently shown that increased oxidative phosphorylation, as reflected by increased mitochondrial activity, together with impairment of the mitochondrial stress response, can severely compromise hematopoietic stem cell (HSC) regeneration. Here we show that the NAD$^{+}$
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Creators (Authors)
- Vannini, Nicola
- Campos, Vasco
- Girotra, Mukul
- Trachsel, Vincent
- Rojas-Sutterlin, Shanti
- Tratwal, Josefine
- Ragusa, Simone
- Stefanidis, Evangelos
- Ryu, Dongryeol
- Rainer, Pernille Y
- Nikitin, Gena
- Giger, Sonja
- Li, Terytty Y
- Semilietof, Aikaterini
- Oggier, Aurelien
- Yersin, Yannick
- Tauzin, Loïc
- Pirinen, Eija
- Cheng, Wan-Chen
- Ratajczak, Joanna
- Canto, Carles
- Sizzano, Federico
- Petrova, Tatiana V
- Vanhecke, Dominique
- Zhang, Lianjun
- Romero, Pedro
- Nahimana, Aimable
- Cherix, Stephane
- Duchosal, Michel A
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Citations
Vannini, N., Campos, V., Girotra, M., Trachsel, V., Rojas-Sutterlin, S., Tratwal, J., Ragusa, S., Stefanidis, E., Ryu, D., Rainer, P. Y., Nikitin, G., Giger, S., Li, T. Y., Semilietof, A., Oggier, A., Yersin, Y., Tauzin, L., Pirinen, E., Cheng, W.-C., … Duchosal, M. A. (2019). The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance. Cell Stem Cell, 24(3), 405-418.e7. https://doi.org/10.1016/j.stem.2019.02.012
