Publication: Age-Dependency of Location of Epileptic Foci in "Continuous Spike-and-Waves during Sleep": A Parallel to the Posterior-Anterior Trajectory of Slow Wave Activity
Age-Dependency of Location of Epileptic Foci in "Continuous Spike-and-Waves during Sleep": A Parallel to the Posterior-Anterior Trajectory of Slow Wave Activity
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Heinzle, B. K. B., Bast, T., Critelli, H., Huber, R., & Schmitt, B. (2016). Age-Dependency of Location of Epileptic Foci in “Continuous Spike-and-Waves during Sleep”: A Parallel to the Posterior-Anterior Trajectory of Slow Wave Activity. Neuropediatrics, 48, 036–041. https://doi.org/10.1055/s-0036-1593989
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Background: Epileptic encephalopathy with continuous spike-and-waves during sleep (CSWS) occurs during childhood and is characterized by an activation of spike wave complexes during slow wave sleep. The location of epileptic foci is variable, as is etiology. A relationship between the epileptic focus and age has been shown in various focal epilepsies following a posterior-anterior trajectory, and a link to brain maturation has been proposed.We hypothesize that in CSWS, maximal spike wave activity, corresponding to the epileptic focus,
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Heinzle, B. K. B., Bast, T., Critelli, H., Huber, R., & Schmitt, B. (2016). Age-Dependency of Location of Epileptic Foci in “Continuous Spike-and-Waves during Sleep”: A Parallel to the Posterior-Anterior Trajectory of Slow Wave Activity. Neuropediatrics, 48, 036–041. https://doi.org/10.1055/s-0036-1593989