Publication: The SLC7A7 Transporter Identifies Microglial Precursors prior to Entry into the Brain
The SLC7A7 Transporter Identifies Microglial Precursors prior to Entry into the Brain
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Rossi, F., Casano, A. M., Henke, K., Richter, K., & Peri, F. (2015). The SLC7A7 Transporter Identifies Microglial Precursors prior to Entry into the Brain. Cell Reports, 11(7), 1008–1017. https://doi.org/10.1016/j.celrep.2015.04.028
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During development, macrophages invade organs to establish phenotypically and transcriptionally distinct tissue-resident populations. How they invade and colonize these organs is unclear. In particular, it remains to be established whether they arise from naive equivalents that colonize organs randomly or whether there are committed macrophages that follow pre-determined migration paths. Here, by using a combination of genetics and imaging approaches in the zebrafish embryo, we have addressed how macrophages colonize the brain to beco
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Rossi, F., Casano, A. M., Henke, K., Richter, K., & Peri, F. (2015). The SLC7A7 Transporter Identifies Microglial Precursors prior to Entry into the Brain. Cell Reports, 11(7), 1008–1017. https://doi.org/10.1016/j.celrep.2015.04.028