Publication: Serotonin 2A receptor signaling underlies LSD-induced alteration of the neural response to dynamic changes in music
Serotonin 2A receptor signaling underlies LSD-induced alteration of the neural response to dynamic changes in music
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Barrett, F. S., Preller, K. H., Herdener, M., Janata, P., & Vollenweider, F. X. (2018). Serotonin 2A receptor signaling underlies LSD-induced alteration of the neural response to dynamic changes in music. Cerebral Cortex, 28(11), 3939–3950. https://doi.org/10.1093/cercor/bhx257
Abstract
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Abstract
Classic psychedelic drugs (serotonin 2A, or 5HT2A, receptor agonists) have notable effects on music listening. In the current report, blood oxygen level-dependent (BOLD) signal was collected during music listening in 25 healthy adults after administration of placebo, lysergic acid diethylamide (LSD), and LSD pretreated with the 5HT2A antagonist ketanserin, to investigate the role of 5HT2A receptor signaling in the neural response to the time-varying tonal structure of music. Tonality-tracking analysis of BOLD data revealed that 5HT2A
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- Barrett, Frederick S
- Preller, Katrin H
- Herdener, Marcus
- Janata, Petr
- Vollenweider, Franz X
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Barrett, F. S., Preller, K. H., Herdener, M., Janata, P., & Vollenweider, F. X. (2018). Serotonin 2A receptor signaling underlies LSD-induced alteration of the neural response to dynamic changes in music. Cerebral Cortex, 28(11), 3939–3950. https://doi.org/10.1093/cercor/bhx257