Publication:

Transcription factor c-Myb: novel prognostic factor in osteosarcoma

Date

Date

Date
2022
Journal Article
Published version

Citations

Citation copied

Říhová, K., Dúcka, M., Zambo, I. S., Vymětalová, L., Šrámek, M., Trčka, F., Verner, J., Drápela, S., Fedr, R., Suchánková, T., Pavlatovská, B., Ondroušková, E., Kubelková, I., Zapletalová, D., Tuček, Š., Múdry, P., Krákorová, D. A., Knopfová, L., Šmarda, J., … Beneš, P. (2022). Transcription factor c-Myb: novel prognostic factor in osteosarcoma. Clinical & Experimental Metastasis, 39(2), 375–390. https://doi.org/10.1007/s10585-021-10145-4

Abstract

Abstract

Abstract

The transcription factor c-Myb is an oncoprotein promoting cell proliferation and survival when aberrantly activated/expressed, thus contributing to malignant transformation. Overexpression of c-Myb has been found in leukemias, breast, colon and adenoid cystic carcinoma. Recent studies revealed its expression also in osteosarcoma cell lines and suggested its functional importance during bone development. However, the relevance of c-Myb in control of osteosarcoma progression remains unknown. A retrospective clinical study was carried o

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50 since deposited on 2023-02-01
Acq. date: 2025-11-14

Additional indexing

Creators (Authors)

  • Říhová, Kamila
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  • Dúcka, Monika
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  • Zambo, Iva Staniczková
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  • Vymětalová, Ladislava
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  • Šrámek, Martin
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  • Trčka, Filip
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  • Verner, Jan
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  • Drápela, Stanislav
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  • Fedr, Radek
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  • Suchánková, Tereza
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  • Pavlatovská, Barbora
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  • Ondroušková, Eva
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  • Kubelková, Irena
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  • Zapletalová, Danica
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  • Tuček, Štěpán
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  • Múdry, Peter
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  • Krákorová, Dagmar Adámková
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  • Knopfová, Lucia
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  • Šmarda, Jan
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  • Souček, Karel
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  • Borsig, Lubor
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  • Beneš, Petr
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Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
39

Number

Number

Number
2

Page range/Item number

Page range/Item number

Page range/Item number
375

Page end

Page end

Page end
390

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2022-04-01

Date available

Date available

Date available
2023-02-01

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
0262-0898

OA Status

OA Status

OA Status
Closed

PubMed ID

PubMed ID

PubMed ID

Metrics

Views

50 since deposited on 2023-02-01
Acq. date: 2025-11-14

Citations

Citation copied

Říhová, K., Dúcka, M., Zambo, I. S., Vymětalová, L., Šrámek, M., Trčka, F., Verner, J., Drápela, S., Fedr, R., Suchánková, T., Pavlatovská, B., Ondroušková, E., Kubelková, I., Zapletalová, D., Tuček, Š., Múdry, P., Krákorová, D. A., Knopfová, L., Šmarda, J., … Beneš, P. (2022). Transcription factor c-Myb: novel prognostic factor in osteosarcoma. Clinical & Experimental Metastasis, 39(2), 375–390. https://doi.org/10.1007/s10585-021-10145-4

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