Publication: Preparation of Indolenines via Nucleophilic Aromatic Substitution and Synthesis of Mangrolide Hybrids
Preparation of Indolenines via Nucleophilic Aromatic Substitution and Synthesis of Mangrolide Hybrids
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Roesslein, J. (2021). Preparation of Indolenines via Nucleophilic Aromatic Substitution and Synthesis of Mangrolide Hybrids. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-215273
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Within this PhD thesis two different areas of organic chemistry, heterocycles and antibiotics, will be discussed. In the first part a new method for the synthesis of indolenine, a benzo-fused N-heterocycle, will be introduced and in the second part the total synthesis of the antibiotic mangrolide hybrids will be presented. Chapter 1: Heterocycles are important building blocks in natural products and drug development. Especially the N-benzo-fused heterocyclic indole and indolenine scaffolds are key in this area. A new method for the sy
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Roesslein, J. (2021). Preparation of Indolenines via Nucleophilic Aromatic Substitution and Synthesis of Mangrolide Hybrids. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-215273
