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Assessment of the Role of Endothelial mTORC2 in FGF2-induced Angiogenesis in vivo

Date

Date

Date
2015
Dissertation

Citations

Citation copied

Georgiopoulou, S. (2015). Assessment of the Role of Endothelial mTORC2 in FGF2-induced Angiogenesis in vivo. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-114847

Abstract

Abstract

Abstract

Angiogenesis is a process where new capillaries are formed from pre-existing ones. It involves endothelial cell activation, extracellular matrix degradation, endothelial cell proliferation and migration and fusion with neighboring sprouts. Stabilization and lumen formation of the new capillary are the last steps of sprouting angiogenesis. Sprouting angiogenesis is one the most prominent mechanism of tumor vascularization and is a growth factor-driven process with FGF2 and VEGF being the key regulators. The mTOR signaling pathway is a

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141 since deposited on 2015-11-17
Acq. date: 2025-11-12

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518 since deposited on 2015-11-17
Acq. date: 2025-11-12

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Creators (Authors)

  • Georgiopoulou, Stavroula

Institution

Institution

Institution

Faculty

Faculty

Faculty
Faculty of Medicine

Item Type

Item Type

Item Type
Dissertation

Referees

  • Gassmann, Max
  • Grimm, Christian
  • Christofori, Gerhard
  • Battegay, Edouard
  • Humar, Rok

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2015

Date available

Date available

Date available
2015-11-17

OA Status

OA Status

OA Status
Green

Metrics

Downloads

141 since deposited on 2015-11-17
Acq. date: 2025-11-12

Views

518 since deposited on 2015-11-17
Acq. date: 2025-11-12

Citations

Citations

Citation copied

Georgiopoulou, S. (2015). Assessment of the Role of Endothelial mTORC2 in FGF2-induced Angiogenesis in vivo. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-114847

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