Publication: DAPT Enhances the Apoptosis of Human Tongue Carcinoma Cells
DAPT Enhances the Apoptosis of Human Tongue Carcinoma Cells
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Grottkau, B. E., Chen, X., Friedrich, C. C., Yang, X., Jing, W., Wu, Y., Cai, X., Liu, Y., Huang, Y., & Lin, Y. (2009). DAPT Enhances the Apoptosis of Human Tongue Carcinoma Cells. International Journal of Oral Science, 1, 81–89. https://doi.org/10.4248/ijos.08025
Abstract
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Abstract
Aim To investigate the effect of DAPT (γ‐secretase inhibitor) on the growth of human tongue carcinoma cells and to determine the molecular mechanism to enable the potential application of DAPT to the treatment of tongue carcinoma. Methodology Human tongue carcinoma Tca8113 cells were cultured with DAPT. Cell growth was determined using Indigotic Reduction method. The cell cycle and apoptosis were analyzed by flow cytometry. Real‐time PCR and Immuno‐Fluorescence (IF) were employed to determine the intracellular expression levels. Resul
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- Grottkau, Brian E
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Grottkau, B. E., Chen, X., Friedrich, C. C., Yang, X., Jing, W., Wu, Y., Cai, X., Liu, Y., Huang, Y., & Lin, Y. (2009). DAPT Enhances the Apoptosis of Human Tongue Carcinoma Cells. International Journal of Oral Science, 1, 81–89. https://doi.org/10.4248/ijos.08025
