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Publication:

Choroid plexus LAT2 and SNAT3 as partners in CSF amino acid homeostasis maintenance

Date

Date

Date
2020
Journal Article
Published version

Citations

Citation copied

Dolgodilina, E., Camargo, S. M., Roth, E., Herzog, B., Nunes, V., Palacín, M., & Verrey, F. (2020). Choroid plexus LAT2 and SNAT3 as partners in CSF amino acid homeostasis maintenance. Fluids and Barriers of the CNS, 17, 17. https://doi.org/10.1186/s12987-020-0178-x

Abstract

Abstract

Abstract

BACKGROUND Cerebrospinal fluid (CSF) is mainly produced by the choroid plexus (CP) located in brain ventricles. Although derived from blood plasma, it is nearly protein-free (~ 250-fold less) and contains about 2-20-fold less free amino acids, with the exception of glutamine (Gln) which is nearly equal. The aim of this study was to determine which amino acid transporters are expressed in mouse CP epithelium in order to gain understanding about how this barrier maintains the observed amino acid concentration gradient. METHODS Expressio

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27 since deposited on 2020-06-04
Acq. date: 2025-11-09

Views

95 since deposited on 2020-06-04
Acq. date: 2025-11-09

Additional indexing

Creators (Authors)

  • Dolgodilina, Elena
    affiliation.icon.alt
  • Camargo, Simone M
    affiliation.icon.alt
  • Roth, Eva
    affiliation.icon.alt
  • Herzog, Brigitte
    affiliation.icon.alt
  • Nunes, Virginia
    affiliation.icon.alt
  • Palacín, Manuel
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
17

Page Range

Page Range

Page Range
17

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2020-02-11

Date available

Date available

Date available
2020-06-04

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
2045-8118

OA Status

OA Status

OA Status
Gold

Free Access at

Free Access at

Free Access at
Pubmed ID

PubMed ID

PubMed ID

PubMed ID

Metrics

Downloads

27 since deposited on 2020-06-04
Acq. date: 2025-11-09

Views

95 since deposited on 2020-06-04
Acq. date: 2025-11-09

Citations

Citation copied

Dolgodilina, E., Camargo, S. M., Roth, E., Herzog, B., Nunes, V., Palacín, M., & Verrey, F. (2020). Choroid plexus LAT2 and SNAT3 as partners in CSF amino acid homeostasis maintenance. Fluids and Barriers of the CNS, 17, 17. https://doi.org/10.1186/s12987-020-0178-x

Gold Open Access
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