Publication: HIV-1 Envelope Plasticity and Its Interplay with Broad Neutralizing Antibody Activity
HIV-1 Envelope Plasticity and Its Interplay with Broad Neutralizing Antibody Activity
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Foulkes, C. (2024). HIV-1 Envelope Plasticity and Its Interplay with Broad Neutralizing Antibody Activity. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-258838
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Over the past several decades, the development of a cost-effective HIV-1 vaccine has faced various significant challenges. All currently approved antiviral vaccines work by eliciting protective antibody responses. These antibodies, to be an effective force against HIV-1 infection, must impede the entry process by binding to the viral envelope (Env) glycoprotein. This glycoprotein plays a critical role in facilitating the attachment of the virus to target cells via the cellular CD4 receptor and enabling membrane fusion. HIV-1 has devel
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Foulkes, C. (2024). HIV-1 Envelope Plasticity and Its Interplay with Broad Neutralizing Antibody Activity. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-258838
