Microcirculatory Monitoring in Children with Congenital Heart Disease Before and After Cardiac Surgery

Erdem, Özge; de Graaff, Jurgen C; Hilty, Matthias P; Kraemer, Ulrike S; de Liefde, Inge I; van Rosmalen, Joost; Ince, Can; Tibboel, Dick; Kuiper, Jan Willem

doi:10.1007/s12265-023-10407-4

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Erdem, Ö., de Graaff, J. C., Hilty, M. P., Kraemer, U. S., de Liefde, I. I., van Rosmalen, J., Ince, C., Tibboel, D., & Kuiper, J. W. (2023). Microcirculatory Monitoring in Children with Congenital Heart Disease Before and After Cardiac Surgery. Journal of Cardiovascular Translational Research, 16(6), 1333–1342. https://doi.org/10.1007/s12265-023-10407-4

Abstract

In this prospective observational study, we investigated whether congenital heart disease (CHD) affects the microcirculation and whether the microcirculation is altered following cardiac surgery with cardiopulmonary bypass (CPB). Thirty-eight children with CHD undergoing cardiac surgery with CPB and 35 children undergoing elective, non-cardiac surgery were included. Repeated non-invasive sublingual microcirculatory measurements were performed with handheld vital microscopy. Before surgery, children with CHD showed similar perfused ves