Publication: Intravenous immunoglobulin treatment of the complex regional pain syndrome: a randomized trial
Intravenous immunoglobulin treatment of the complex regional pain syndrome: a randomized trial
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Goebel, A., Baranowski, A., Maurer, K., Ghiai, A., McCabe, C., & Ambler, G. (2010). Intravenous immunoglobulin treatment of the complex regional pain syndrome: a randomized trial. Annals of Internal Medicine, 152(3), 152–158. https://doi.org/10.7326/0003-4819-152-3-201002020-00006
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BACKGROUND: Treatment of long-standing complex regional pain syndrome (CRPS) is empirical and often of limited efficacy. Preliminary data suggest that the immune system is involved in sustaining this condition and that treatment with low-dose intravenous immunoglobulin (IVIG) may substantially reduce pain in some patients. OBJECTIVE: To evaluate the efficacy of IVIG in patients with longstanding CRPS under randomized, controlled conditions. DESIGN: A randomized, double-blind, placebo-controlled crossover trial. (National Research Regi
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Goebel, A., Baranowski, A., Maurer, K., Ghiai, A., McCabe, C., & Ambler, G. (2010). Intravenous immunoglobulin treatment of the complex regional pain syndrome: a randomized trial. Annals of Internal Medicine, 152(3), 152–158. https://doi.org/10.7326/0003-4819-152-3-201002020-00006