Publication: Loss of LAT1 sex-dependently delays recovery after caerulein-induced acute pancreatitis
Loss of LAT1 sex-dependently delays recovery after caerulein-induced acute pancreatitis
Date
Date
Date
Citations
Hagen, C. M., Roth, E., Graf, T. R., Verrey, F., Graf, R., Gupta, A., Pellegrini, G., Poncet, N., & Camargo, S. M. R. (2022). Loss of LAT1 sex-dependently delays recovery after caerulein-induced acute pancreatitis. World Journal of Gastroenterology, 28(10), 1024–1054. https://doi.org/10.3748/wjg.v28.i10.1024
Abstract
Abstract
Abstract
Background: The expression of amino acid transporters is known to vary during acute pancreatitis (AP) except for LAT1 (slc7a5), the expression of which remains stable. LAT1 supports cell growth by importing leucine and thereby stimulates mammalian target of rapamycin (mTOR) activity, a phenomenon often observed in cancer cells. The mechanisms by which LAT1 influences physiological and pathophysiological processes and affects disease progression in the pancreas are not yet known. Aim: To evaluate the role of LAT1 in the development of
Additional indexing
Creators (Authors)
- Hagen, Cristina M
- Roth, Eva
- Graf, Theresia Reding
- Verrey, François
- Graf, Rolf
- Gupta, Anurag
- Pellegrini, Giovanni
- Poncet, Nadège
- Camargo, Simone Mafalda Rodrigues
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
Keywords
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Free Access at
Free Access at
Free Access at
Publisher DOI
Citations
Hagen, C. M., Roth, E., Graf, T. R., Verrey, F., Graf, R., Gupta, A., Pellegrini, G., Poncet, N., & Camargo, S. M. R. (2022). Loss of LAT1 sex-dependently delays recovery after caerulein-induced acute pancreatitis. World Journal of Gastroenterology, 28(10), 1024–1054. https://doi.org/10.3748/wjg.v28.i10.1024
