Publication: Tissue-specific differentiation of a circulating CCR9- pDC-like common dendritic cell precursor
Tissue-specific differentiation of a circulating CCR9- pDC-like common dendritic cell precursor
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Schlitzer, A., Heiseke, A. F., Einwächter, H., Reindl, W., Schiemann, M., Manta, C.-P., See, P., Niess, J.-H., Suter, T., Ginhoux, F., & Krug, A. B. (2012). Tissue-specific differentiation of a circulating CCR9- pDC-like common dendritic cell precursor. Blood, 119(25), 6063–6071. https://doi.org/10.1182/blood-2012-03-418400
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The ontogenic relationship between the common dendritic cell (DC) progenitor (CDP), the committed conventional DC precursor (pre-cDC), and cDC subpopulations in lymphoid and nonlymphoid tissues has been largely unraveled. In contrast, the sequential steps of plasmacytoid DC (pDC) development are less defined, and it is unknown at which developmental stage and location final commitment to the pDC lineage occurs. Here we show that CCR9(-) pDCs from murine BM which enter the circulation and peripheral tissues have a common DC precursor f
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- Schlitzer, Andreas
- Heiseke, Alexander F
- Einwächter, Henrik
- Reindl, Wolfgang
- Schiemann, Matthias
- Manta, Calin-Petru
- See, Peter
- Niess, Jan-Hendrik
- Suter, Tobias
- Ginhoux, Florent
- Krug, Anne B
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Schlitzer, A., Heiseke, A. F., Einwächter, H., Reindl, W., Schiemann, M., Manta, C.-P., See, P., Niess, J.-H., Suter, T., Ginhoux, F., & Krug, A. B. (2012). Tissue-specific differentiation of a circulating CCR9- pDC-like common dendritic cell precursor. Blood, 119(25), 6063–6071. https://doi.org/10.1182/blood-2012-03-418400
