Publication: Mitochondrial disease, mitophagy, and cellular distress in methylmalonic acidemia
Mitochondrial disease, mitophagy, and cellular distress in methylmalonic acidemia
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Luciani, A., Denley, M. C. S., Govers, L. P., Sorrentino, V., & Froese, D. S. (2021). Mitochondrial disease, mitophagy, and cellular distress in methylmalonic acidemia. Cellular and Molecular Life Sciences, 78(21–22), 6851–6867. https://doi.org/10.1007/s00018-021-03934-3
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Mitochondria—the intracellular powerhouse in which nutrients are converted into energy in the form of ATP or heat—are highly dynamic, double-membraned organelles that harness a plethora of cellular functions that sustain energy metabolism and homeostasis. Exciting new discoveries now indicate that the maintenance of this ever changing and functionally pleiotropic organelle is particularly relevant in terminally differentiated cells that are highly dependent on aerobic metabolism. Given the central role in maintaining metabolic and phy
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- Luciani, Alessandro
- Denley, Matthew C S
- Govers, Larissa P
- Sorrentino, Vincenzo
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Luciani, A., Denley, M. C. S., Govers, L. P., Sorrentino, V., & Froese, D. S. (2021). Mitochondrial disease, mitophagy, and cellular distress in methylmalonic acidemia. Cellular and Molecular Life Sciences, 78(21–22), 6851–6867. https://doi.org/10.1007/s00018-021-03934-3
