Publication: Fetal loss in homozygous mutant Norrie disease mice: A new role of Norrin in reproduction
Fetal loss in homozygous mutant Norrie disease mice: A new role of Norrin in reproduction
Date
Date
Date
Citations
Luhmann, U. F. O., Meunier, D., Shi, W., Lüttges, A., Pfarrer, C., Fundele, R., & Berger, W. (2005). Fetal loss in homozygous mutant Norrie disease mice: A new role of Norrin in reproduction. Genesis, 42, 253–262. https://doi.org/10.1002/gene.20141
Abstract
Abstract
Abstract
Mutations in the Norrie disease pseudoglioma gene (NDP) are known to cause X-linked recessive Norrie disease. In addition, NDP mutations have been found in other vasoproliferative retinopathies such as familial exudative vitreoretinopathy, retinopathy of prematurity, and Coats disease, suggesting a role for Norrin in vascular development. Here we report that female mice homozygous for the Norrie disease pseudoglioma homolog (Ndph) knockout allele exhibit almost complete infertility, while heterozygous females and hemizygous males are
Additional indexing
Creators (Authors)
- Luhmann, Ulrich F O
- Meunier, Dominique
- Shi, Wei
- Lüttges, Angela
- Pfarrer, Christiane
- Fundele, Reinald
- Berger, Wolfgang
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Keywords
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Publisher DOI
Citations
Luhmann, U. F. O., Meunier, D., Shi, W., Lüttges, A., Pfarrer, C., Fundele, R., & Berger, W. (2005). Fetal loss in homozygous mutant Norrie disease mice: A new role of Norrin in reproduction. Genesis, 42, 253–262. https://doi.org/10.1002/gene.20141
