Publication: A defect in the mitochondrial protein Mpv17 underlies the transparent casper zebrafish
A defect in the mitochondrial protein Mpv17 underlies the transparent casper zebrafish
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D’Agati, G., Beltre, R., Sessa, A., Burger, A., Zhou, Y., Mosimann, C., & White, R. M. (2017). A defect in the mitochondrial protein Mpv17 underlies the transparent casper zebrafish. Developmental Biology, 430(1), 11–17. https://doi.org/10.1016/j.ydbio.2017.07.017
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Abstract
The casper strain of zebrafish is widely used in studies ranging from cancer to neuroscience. casper offers the advantage of relative transparency throughout adulthood, making it particularly useful for in vivo imaging by epifluorescence, confocal, and light sheet microscopy. casper was developed by selective breeding of two previously described recessive pigment mutants: 1) nacre, which harbors an inactivating mutation of the mitfa gene, rendering the fish devoid of pigmented melanocytes; and 2) roy orbison, a mutant with a so-far un
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- D'Agati, Gianluca
- Beltre, Rosanna
- Sessa, Anna
- Burger, Alexa
- Zhou, Yi
- Mosimann, Christian
- White, Richard M
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D’Agati, G., Beltre, R., Sessa, A., Burger, A., Zhou, Y., Mosimann, C., & White, R. M. (2017). A defect in the mitochondrial protein Mpv17 underlies the transparent casper zebrafish. Developmental Biology, 430(1), 11–17. https://doi.org/10.1016/j.ydbio.2017.07.017