Publication: Toward three-dimensional in vitro models to study neurovascular unit functions in health and disease
Toward three-dimensional in vitro models to study neurovascular unit functions in health and disease
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Caffrey, T. M., Button, E. B., & Robert, J. (2021). Toward three-dimensional in vitro models to study neurovascular unit functions in health and disease. Neural Regeneration Research, 16(11), 2132–2140. https://doi.org/10.4103/1673-5374.310671
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The high metabolic demands of the brain require an efficient vascular system to be coupled with neural activity to supply adequate nutrients and oxygen. This supply is coordinated by the action of neurons, glial and vascular cells, known collectively as the neurovascular unit, which temporally and spatially regulate local cerebral blood flow through a process known as neurovascular coupling. In many neurodegenerative diseases, changes in functions of the neurovascular unit not only impair neurovascular coupling but also permeability o
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Caffrey, T. M., Button, E. B., & Robert, J. (2021). Toward three-dimensional in vitro models to study neurovascular unit functions in health and disease. Neural Regeneration Research, 16(11), 2132–2140. https://doi.org/10.4103/1673-5374.310671