Publication: Laminin α4 Expression in Human Adipose Tissue Depots and Its Association with Obesity and Obesity Related Traits
Laminin α4 Expression in Human Adipose Tissue Depots and Its Association with Obesity and Obesity Related Traits
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Hagemann, T., Czechowski, P., Ghosh, A., Sun, W., Dong, H., Noé, F., Wolfrum, C., Blüher, M., & Hoffmann, A. (2023). Laminin α4 Expression in Human Adipose Tissue Depots and Its Association with Obesity and Obesity Related Traits. Biomedicines, 11(10), 2806. https://doi.org/10.3390/biomedicines11102806
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Laminin α4 (LAMA4) is one of the main structural adipocyte basement membrane (BM) components that is upregulated during adipogenesis and related to obesity in mice and humans. We conducted RNA-seq-based gene expression analysis of LAMA4 in abdominal subcutaneous (SC) and visceral (VIS) adipose tissue (AT) depots across three human sub-cohorts of the Leipzig Obesity BioBank (LOBB) to explore the relationship between LAMA4 expression and obesity (N = 1479) in the context of weight loss (N = 65) and metabolic health (N = 42). We found si
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- Hagemann, Tobias
- Czechowski, Paul
- Ghosh, Adhideb
- Sun, Wenfei
- Dong, Hua
- Noé, Falko
- Wolfrum, Christian
- Blüher, Matthias
- Hoffmann, Anne
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Hagemann, T., Czechowski, P., Ghosh, A., Sun, W., Dong, H., Noé, F., Wolfrum, C., Blüher, M., & Hoffmann, A. (2023). Laminin α4 Expression in Human Adipose Tissue Depots and Its Association with Obesity and Obesity Related Traits. Biomedicines, 11(10), 2806. https://doi.org/10.3390/biomedicines11102806
