Publication: A Novel Combination of Host Protein Biomarkers to Distinguish Bacterial From Viral Infections in Febrile Children in Emergency Care
A Novel Combination of Host Protein Biomarkers to Distinguish Bacterial From Viral Infections in Febrile Children in Emergency Care
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Tan, C. D., van den Broek, B., Womersley, R. S., Kaforou, M., Hagedoorn, N. N., van der Flier, M., Jackson, H., Moll, H. A., Snijder, R., de Jonge, M. I., Vermont, C. L., & PERFORM Consortium. (2023). A Novel Combination of Host Protein Biomarkers to Distinguish Bacterial From Viral Infections in Febrile Children in Emergency Care. The Pediatric Infectious Disease Journal, 42(7), e235–e242. https://doi.org/10.1097/inf.0000000000003952
Abstract
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Background: Distinguishing bacterial and viral infections based on clinical symptoms in febrile children attending the emergency department (ED) is challenging. The aim of this study is to determine a novel combination of host protein biomarkers and to assess its performance in distinguishing between bacterial and viral infection in febrile children attending EDs.
Methods: A literature search was performed to identify blood protein biomarkers able to distinguish bacterial and viral infections (May 2015-May 2019). We selected 7 protei
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- Tan, Chantal D
- van den Broek, Bryan
- Womersley, Rebecca S
- Kaforou, Myrsini
- Hagedoorn, Nienke N
- van der Flier, Michiel
- Jackson, Heather
- Moll, Henriette A
- Snijder, Rozemarijn
- de Jonge, Marien I
- Vermont, Clementien L
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Tan, C. D., van den Broek, B., Womersley, R. S., Kaforou, M., Hagedoorn, N. N., van der Flier, M., Jackson, H., Moll, H. A., Snijder, R., de Jonge, M. I., Vermont, C. L., & PERFORM Consortium. (2023). A Novel Combination of Host Protein Biomarkers to Distinguish Bacterial From Viral Infections in Febrile Children in Emergency Care. The Pediatric Infectious Disease Journal, 42(7), e235–e242. https://doi.org/10.1097/inf.0000000000003952
