Publication: Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice
Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice
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Meyer, U., Nyffeler, M., Yee, B. K., Knuesel, I., & Feldon, J. (2008). Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice. Brain, Behavior, and Immunity, 22(4), 469–486. https://doi.org/10.1016/j.bbi.2007.09.012
Abstract
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Maternal infection during pregnancy increases the risk for neurodevelopmental disorders such as schizophrenia and autism in the offspring. This association appears to be critically dependent on the precise prenatal timing. However, the extent to which distinct adult psychopathological and neuropathological traits may be sensitive to the precise times of prenatal immune activation remains to be further characterized. Here, we evaluated in a mouse model of prenatal immune challenge by the viral mimic, polyriboinosinic-polyribocytidilic
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- Meyer, U
- Nyffeler, M
- Yee, B K
- Knuesel, I
- Feldon, J
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Citations
Meyer, U., Nyffeler, M., Yee, B. K., Knuesel, I., & Feldon, J. (2008). Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice. Brain, Behavior, and Immunity, 22(4), 469–486. https://doi.org/10.1016/j.bbi.2007.09.012
