Publication: Cortisol excess in patients with primary aldosteronism impacts on left ventricular hypertrophy
Cortisol excess in patients with primary aldosteronism impacts on left ventricular hypertrophy
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Adolf, C., Köhler, A., Franke, A., Lang, K., Riester, A., Löw, A., Heinrich, D. A., Bidlingmaier, M., Treitl, M., Ladurner, R., Beuschlein, F., Arlt, W., & Reincke, M. (2018). Cortisol excess in patients with primary aldosteronism impacts on left ventricular hypertrophy. Journal of Clinical Endocrinology & Metabolism, 103(12), 4543–4552. https://doi.org/10.1210/jc.2018-00617
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Context Primary aldosteronism (PA) represents the most frequent form of endocrine hypertension. Hyperaldosteronism and hypercortisolism both induce excessive left ventricular hypertrophy (LVH) compared to matched essential hypertensives. In recent studies frequent co-secretion of cortisol and aldosterone has been reported in PA patients. Objective Our aim was to investigate the impact of cortisol co-secretion on left ventricular hypertrophy in PA patients. We determined 24-h excretion of mineralocorticoids and glucocorticoids by ga
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Adolf, C., Köhler, A., Franke, A., Lang, K., Riester, A., Löw, A., Heinrich, D. A., Bidlingmaier, M., Treitl, M., Ladurner, R., Beuschlein, F., Arlt, W., & Reincke, M. (2018). Cortisol excess in patients with primary aldosteronism impacts on left ventricular hypertrophy. Journal of Clinical Endocrinology & Metabolism, 103(12), 4543–4552. https://doi.org/10.1210/jc.2018-00617