Publication: Osteopontin levels correlate with severity of diabetic cardiomyopathy in early stage of diabetes
Osteopontin levels correlate with severity of diabetic cardiomyopathy in early stage of diabetes
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Scuricini, A., Andreozzi, F., Sgura, C., Ministrini, S., Bertolotto, M., Ramoni, D., Liberale, L., Camici, G. G., Mannino, G. C., Succurro, E., Armentaro, G., Fiorentino, T. V., Cassano, V., Miceli, S., Perticone, M., Rubino, M., Sesti, G., Montecucco, F., Sciacqua, A., & Carbone, F. (2023). Osteopontin levels correlate with severity of diabetic cardiomyopathy in early stage of diabetes. Diabetes Research and Clinical Practice, 203, 110885. https://doi.org/10.1016/j.diabres.2023.110885
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Diabetic cardiomyopathy (DbCM) is characterized by restrictive pattern and consistent risk of overt heart failure. We here focused osteopontin (OPN), which was tested independently associated with left ventricular diastolic dysfunction (LVDD). Overall, OPN increased with DbCM severity according with the presence of left atrial dilatation, LV hypertrophy and LVDD.
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Scuricini, A., Andreozzi, F., Sgura, C., Ministrini, S., Bertolotto, M., Ramoni, D., Liberale, L., Camici, G. G., Mannino, G. C., Succurro, E., Armentaro, G., Fiorentino, T. V., Cassano, V., Miceli, S., Perticone, M., Rubino, M., Sesti, G., Montecucco, F., Sciacqua, A., & Carbone, F. (2023). Osteopontin levels correlate with severity of diabetic cardiomyopathy in early stage of diabetes. Diabetes Research and Clinical Practice, 203, 110885. https://doi.org/10.1016/j.diabres.2023.110885