Publication: Questioning the Value of Fluorodeoxyglucose Positron Emission Tomography for Residual Lesions After Chemotherapy for Metastatic Seminoma: Results of an International Global Germ Cell Cancer Group Registry
Questioning the Value of Fluorodeoxyglucose Positron Emission Tomography for Residual Lesions After Chemotherapy for Metastatic Seminoma: Results of an International Global Germ Cell Cancer Group Registry
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Cathomas, R., Klingbiel, D., Bernard, B., Lorch, A., Garcia Del Muro, X., Morelli, F., De Giorgi, U., Fedyanin, M., Oing, C., Sagstuen Haugnes, H., Hentrich, M., Fankhauser, C., Gillessen, S., & Beyer, J. (2018). Questioning the Value of Fluorodeoxyglucose Positron Emission Tomography for Residual Lesions After Chemotherapy for Metastatic Seminoma: Results of an International Global Germ Cell Cancer Group Registry. Journal of Clinical Oncology, 36, 3381–3387. https://doi.org/10.1200/JCO.18.00210
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PURPOSE
Residual lesions after chemotherapy are frequent in metastatic seminoma. Watchful waiting is recommended for lesions < 3 cm as well as for fluorodeoxyglucose (FDG) positron emission tomography (PET)-negative lesions ≥ 3 cm. Information on the optimal management of PET-positive residual lesions ≥ 3 cm is lacking.
PATIENTS AND METHODS
We retrospectively identified 90 patients with metastatic seminoma with PET-positive residual lesions after chemotherapy. Patients with elevated α-fetoprotein or nonseminomatous histology were e
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Cathomas, R., Klingbiel, D., Bernard, B., Lorch, A., Garcia Del Muro, X., Morelli, F., De Giorgi, U., Fedyanin, M., Oing, C., Sagstuen Haugnes, H., Hentrich, M., Fankhauser, C., Gillessen, S., & Beyer, J. (2018). Questioning the Value of Fluorodeoxyglucose Positron Emission Tomography for Residual Lesions After Chemotherapy for Metastatic Seminoma: Results of an International Global Germ Cell Cancer Group Registry. Journal of Clinical Oncology, 36, 3381–3387. https://doi.org/10.1200/JCO.18.00210