Publication: Paracrine effects of mesenchymal stem cells enhance vascular regeneration in ischemic murine skin
Paracrine effects of mesenchymal stem cells enhance vascular regeneration in ischemic murine skin
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Schlosser, S., Dennler, C., Schweizer, R., Eberli, D., Stein, J. V., Enzmann, V., Giovanoli, P., Erni, D., & Plock, J. A. (2012). Paracrine effects of mesenchymal stem cells enhance vascular regeneration in ischemic murine skin. Microvascular Research, 83, 267–675. https://doi.org/10.1016/j.mvr.2012.02.011
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New theories on the regeneration of ischemic vasculature have emerged indicating a pivotal role of adult stem cells. The aim of this study was to investigate homing and hemodynamic effects of circulating bone marrow-derived mesenchymal stem cells (MSCs) in a critically ischemic murine skin flap model. Bone marrow-derived mesenchymal stem cells (Lin(-)CD105(+)) were harvested from GFP(+)-donor mice and transferred to wildtype C57BL/6 mice. Animals receiving GFP(+)-fibroblasts served as a control group. Laser scanning confocal microscop
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- Schlosser, Stefan
- Dennler, Cyrill
- Schweizer, Riccardo
- Eberli, Daniel
- Stein, Jens V
- Enzmann, Volker
- Giovanoli, Pietro
- Erni, Dominique
- Plock, Jan A
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Schlosser, S., Dennler, C., Schweizer, R., Eberli, D., Stein, J. V., Enzmann, V., Giovanoli, P., Erni, D., & Plock, J. A. (2012). Paracrine effects of mesenchymal stem cells enhance vascular regeneration in ischemic murine skin. Microvascular Research, 83, 267–675. https://doi.org/10.1016/j.mvr.2012.02.011