Publication: Amylin sensitivity and secretion following diet-induced obesity in rats
Amylin sensitivity and secretion following diet-induced obesity in rats
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Rossier, M. (2010). Amylin sensitivity and secretion following diet-induced obesity in rats. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-40121
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The aim of this study was to investigate the influence of diet-induced obesity (DIO) and the resulting changes in hormone metabolism, on amylin sensitivity and secretion. Our investigation resulted in the following findings: Study One Findings: After 11 weeks of high fat (HF)-feeding, DIO rats showed a reduced anorectic response to acute amylin (5µg/kg, ip). HF-feeding also increased basal amylin and leptin levels, and total body fat. Conclusion: Long-term HF-feeding decreased sensitivity to exogenous amylin in DIO rats. Study Two Fin
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Rossier, M. (2010). Amylin sensitivity and secretion following diet-induced obesity in rats. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-40121