Publication: Sevoflurane preconditioning protects from posttransplant injury in mouse lung transplantation
Sevoflurane preconditioning protects from posttransplant injury in mouse lung transplantation
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Yamada, Y., Laube, I., Jang, J.-H., Bonvini, J. M., Inci, I., Weder, W., Beck-Schimmer, B., & Jungraithmayr, W. (2017). Sevoflurane preconditioning protects from posttransplant injury in mouse lung transplantation. Journal of Surgical Research, 214, 270–277. https://doi.org/10.1016/j.jss.2017.03.021
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BACKGROUND: Although sevoflurane (Sevo) had been shown to ameliorate posttransplant injury in various organs, data available are inconsistent, particularly in the context of lung transplantation (Tx). We here investigated if preconditioning by Sevo can protect from posttransplant injury regarding both, primary graft dysfunction (PGD) and acute rejection (AR) after experimental lung Tx, thereby focusing on two important clinical outcome parameters. MATERIALS AND METHODS: Three experimental approaches were used: (1) BALB/c mice were pre
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Yamada, Y., Laube, I., Jang, J.-H., Bonvini, J. M., Inci, I., Weder, W., Beck-Schimmer, B., & Jungraithmayr, W. (2017). Sevoflurane preconditioning protects from posttransplant injury in mouse lung transplantation. Journal of Surgical Research, 214, 270–277. https://doi.org/10.1016/j.jss.2017.03.021