Publication: CanIsoNet: a database to study the functional impact of isoform switching events in diseases
CanIsoNet: a database to study the functional impact of isoform switching events in diseases
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Karakulak, T., Szklarczyk, D., Saylan, C. C., Moch, H., von Mering, C., & Kahraman, A. (2023). CanIsoNet: a database to study the functional impact of isoform switching events in diseases. Bioinformatics Advances, 3, vbad050. https://doi.org/10.1093/bioadv/vbad050
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MOTIVATION: Alternative splicing, as an essential regulatory mechanism in normal mammalian cells, is frequently disturbed in cancer and other diseases. Switches in the expression of most dominant alternative isoforms can alter protein interaction networks of associated genes giving rise to disease and disease progression. Here, we present CanIsoNet, a database to view, browse and search isoform switching events in diseases. CanIsoNet is the first webserver that incorporates isoform expression data with STRING interaction networks and
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- Karakulak, Tülay
- Szklarczyk, Damian
- Saylan, Cemil Can
- Moch, Holger
- Kahraman, Abdullah
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Karakulak, T., Szklarczyk, D., Saylan, C. C., Moch, H., von Mering, C., & Kahraman, A. (2023). CanIsoNet: a database to study the functional impact of isoform switching events in diseases. Bioinformatics Advances, 3, vbad050. https://doi.org/10.1093/bioadv/vbad050
