Publication: Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control.
Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control.
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Oldham, S., & Hafen, E. (2003). Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control. Trends in Cell Biology, 13(2), 79–85. https://doi.org/10.1016/S0962-8924(02)00042-9
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'They come in all sizes.' Apart from its origin and use in the clothing industry, this saying reflects the fact that the size of organisms spans an enormous range. Whether destined to be large or small, species grow in an organized fashion to reach their final specified size. For growth to proceed, food must be metabolized to liberate energy in the form of adenosine triphosphate (ATP) and protein building blocks in the form of amino acids. One major orchestrator of this complex growth process in diverse metazoan species is the insulin
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- Oldham, S
- Hafen, E
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Oldham, S., & Hafen, E. (2003). Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control. Trends in Cell Biology, 13(2), 79–85. https://doi.org/10.1016/S0962-8924(02)00042-9