Publication: Microglia states and nomenclature: A field at its crossroads
Microglia states and nomenclature: A field at its crossroads
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Paolicelli, R. C., Sierra, A., Stevens, B., Tremblay, M.-E., Aguzzi, A., et al, Greter, M., Peri, F., & et al. (2022). Microglia states and nomenclature: A field at its crossroads. Neuron, 110(21), 3458–3483. https://doi.org/10.1016/j.neuron.2022.10.020
Abstract
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Abstract
Microglial research has advanced considerably in recent decades yet has been constrained by a rolling series of dichotomies such as "resting versus activated" and "M1 versus M2." This dualistic classification of good or bad microglia is inconsistent with the wide repertoire of microglial states and functions in development, plasticity, aging, and diseases that were elucidated in recent years. New designations continuously arising in an attempt to describe the different microglial states, notably defined using transcriptomics and prote
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- Paolicelli, Rosa C
- Sierra, Amanda
- Stevens, Beth
- Tremblay, Marie-Eve
- Peri, Francesca
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Paolicelli, R. C., Sierra, A., Stevens, B., Tremblay, M.-E., Aguzzi, A., et al, Greter, M., Peri, F., & et al. (2022). Microglia states and nomenclature: A field at its crossroads. Neuron, 110(21), 3458–3483. https://doi.org/10.1016/j.neuron.2022.10.020
