Publication: Urine steroid metabolomics as a novel tool for detection of recurrent adrenocortical carcinoma
Urine steroid metabolomics as a novel tool for detection of recurrent adrenocortical carcinoma
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Chortis, V., Bancos, I., Nijman, T., Beuschlein, F., & et al. (2020). Urine steroid metabolomics as a novel tool for detection of recurrent adrenocortical carcinoma. Journal of Clinical Endocrinology & Metabolism, 105(3), dgz141. https://doi.org/10.1210/clinem/dgz141
Abstract
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Abstract
CONTEXT Urine steroid metabolomics, combining mass spectrometry-based steroid profiling and machine learning, has been described as a novel diagnostic tool for detection of adrenocortical carcinoma (ACC). OBJECTIVE, DESIGN, SETTING This proof-of-concept study evaluated the performance of urine steroid metabolomics as a tool for post-operative recurrence detection after microscopically complete (R0) resection of ACC. PATIENTS AND METHODS 135 patients from 14 clinical centers provided post-operative urine samples, which were analyzed
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Creators (Authors)
- Chortis, Vasileios
- Bancos, Irina
- Nijman, Thomas
- Beuschlein, Felix
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Citations
Chortis, V., Bancos, I., Nijman, T., Beuschlein, F., & et al. (2020). Urine steroid metabolomics as a novel tool for detection of recurrent adrenocortical carcinoma. Journal of Clinical Endocrinology & Metabolism, 105(3), dgz141. https://doi.org/10.1210/clinem/dgz141
