Publication: Aberrant Ganglioside Functions to Underpin Dysregulated Myelination, Insulin Signalling, and Cytokine Expression: Is There a Link and a Room for Therapy?
Aberrant Ganglioside Functions to Underpin Dysregulated Myelination, Insulin Signalling, and Cytokine Expression: Is There a Link and a Room for Therapy?
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Citations
Svirin, E., de Munter, J., Umriukhin, A., Sheveleva, E., Kalueff, A. V., Svistunov, A., Morozov, S., Walitza, S., & Strekalova, T. (2022). Aberrant Ganglioside Functions to Underpin Dysregulated Myelination, Insulin Signalling, and Cytokine Expression: Is There a Link and a Room for Therapy? Biomolecules, 12(10), 1434. https://doi.org/10.3390/biom12101434
Abstract
Abstract
Abstract
Gangliosides are molecules widely present in the plasma membranes of mammalian cells, participating in a variety of processes, including protein organization, transmembrane signalling and cell adhesion. Gangliosides are abundant in the grey matter of the brain, where they are critically involved in postnatal neural development and function. The common precursor of the majority of brain gangliosides, GM3, is formed by the sialylation of lactosylceramide, and four derivatives of its a- and b-series, GM1, GD1a, GD1b and GT1b, constitute
Additional indexing
Creators (Authors)
- Svirin, Evgeniy
- de Munter, Johannes
- Umriukhin, Aleksei
- Sheveleva, Elisaveta
- Kalueff, Allan V
- Svistunov, Andrei
- Morozov, Sergey
- Walitza, Susanne
- Strekalova, Tatyana
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In collections
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H2020
FP7
Grant ID
Grant ID
Grant ID
101007642
120209
Project Title
Project Title
Project Title
PhytoAPP - INNOVATIVE WATER-SOLUBLE PHYTOMATERIAL INHIBITORs FOR ALZHEIMERs AND PARKINSONs DISEASES PREVENTION
CSI - Central Nervous System Imaging
Citations
Svirin, E., de Munter, J., Umriukhin, A., Sheveleva, E., Kalueff, A. V., Svistunov, A., Morozov, S., Walitza, S., & Strekalova, T. (2022). Aberrant Ganglioside Functions to Underpin Dysregulated Myelination, Insulin Signalling, and Cytokine Expression: Is There a Link and a Room for Therapy? Biomolecules, 12(10), 1434. https://doi.org/10.3390/biom12101434
