Publication: Langerin+ DCs regulate innate IL-17 production in the oral mucosa during Candida albicans-mediated infection
Date
Date
Date
2018
Journal Article
Published version
Abstract
Abstract
Abstract
The opportunistic fungal pathogen Candida albicans frequently causes diseases such as oropharyngeal candidiasis (OPC) in immunocompromised individuals. Although it is well appreciated that the cytokine IL-17 is crucial for protective immunity against OPC, the cellular source and the regulation of this cytokine during infection are still a matter of debate. Here, we directly visualized IL-17 production in the tongue of experimentally infected mice, thereby demonstrating that this key cytokine is expressed by three complementary subsets
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Downloads
45 since deposited on 2018-07-20
Acq. date: 2025-11-14
Views
132 since deposited on 2018-07-20
Acq. date: 2025-11-14
Additional indexing
Creators (Authors)
- Sparber, Florian
- Dolowschiak, Tamas
- Mertens, Sarah
- Lauener, Laura
- Clausen, Björn E
- Joller, Nicole
- Stoitzner, Patrizia
- Tussiwand, Roxane
Volume
Volume
Volume
14
Number
Number
Number
5
Page range/Item number
Page range/Item number
Page range/Item number
e1007069
Item Type
Item Type
Item Type
Journal Article
Language
Language
Language
English
Publication date
Publication date
Publication date
2018
Date available
Date available
Date available
2018-07-20
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
1553-7366
OA Status
OA Status
OA Status
Gold
Free Access at
Free Access at
Free Access at
Pubmed ID
Publisher DOI
Metrics
Downloads
45 since deposited on 2018-07-20
Acq. date: 2025-11-14
Views
132 since deposited on 2018-07-20
Acq. date: 2025-11-14
Gold Open Access
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