Publication: Iron deficiency and biomarkers of inflammation: a 3-year prospective analysis of the DO-HEALTH trial
Iron deficiency and biomarkers of inflammation: a 3-year prospective analysis of the DO-HEALTH trial
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Wieczorek, M., Schwarz, F., Sadlon, A., Abderhalden, L. A., de Godoi Rezende Costa Molino, C., Spahn, D. R., Schaer, D. J., Orav, E. J., Egli, A., & Bischoff-Ferrari, H. A. (2022). Iron deficiency and biomarkers of inflammation: a 3-year prospective analysis of the DO-HEALTH trial. Aging Clinical and Experimental Research, 34(3), 515–525. https://doi.org/10.1007/s40520-021-01955-3
Abstract
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Background: The longitudinal association between iron deficiency and inflammatory biomarkers levels has not been fully explored among relatively healthy older adults.
Aims: To assess whether iron deficiency at baseline and at any yearly follow-up time point, with or without anemia, was associated with changes from baseline in high-sensitivity C-reactive protein (hs-CRP) and interleukin-6 (IL-6) levels over 3 years.
Methods: This is a post-hoc observational analysis of DO-HEALTH, a double-blind, randomized controlled trial including
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- Wieczorek, Maud
- Schwarz, Franziska
- Sadlon, Angélique
- Abderhalden, Lauren A
- de Godoi Rezende Costa Molino, Caroline
- Spahn, Donat R
- Schaer, Dominik J
- Orav, E John
- Egli, Andreas
- Bischoff-Ferrari, Heike A
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Wieczorek, M., Schwarz, F., Sadlon, A., Abderhalden, L. A., de Godoi Rezende Costa Molino, C., Spahn, D. R., Schaer, D. J., Orav, E. J., Egli, A., & Bischoff-Ferrari, H. A. (2022). Iron deficiency and biomarkers of inflammation: a 3-year prospective analysis of the DO-HEALTH trial. Aging Clinical and Experimental Research, 34(3), 515–525. https://doi.org/10.1007/s40520-021-01955-3
