Recent achievements and doors opened for coccidian parasite research and development through transcriptomics of enteric sexual stages

Ramakrishnan, Chandra; Smith, Nicholas C

doi:10.1016/j.molbiopara.2021.111373

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Ramakrishnan, C., & Smith, N. C. (2021). Recent achievements and doors opened for coccidian parasite research and development through transcriptomics of enteric sexual stages. Molecular and Biochemical Parasitology, 243, 111373. https://doi.org/10.1016/j.molbiopara.2021.111373

Abstract

The Coccidia is the largest group of parasites within the Apicomplexa, a phylum of unicellular, obligate parasites characterized by the possession of an apical complex of organelles and structures in the asexual stages of their life cycles, as well as by a sexual reproductive phase that occurs enterically in host animals. Coccidian sexual reproduction involves morphologically distinct microgametes and macrogametes that combine to form a diploid zygote and, ultimately, following meiosis and mitosis, haploid, infectious sporozoites, ins