Publication: Clinical evaluation of pimecrolimus eye drops for treatment of canine keratoconjunctivitis sicca: A comparison with cyclosporine A
Clinical evaluation of pimecrolimus eye drops for treatment of canine keratoconjunctivitis sicca: A comparison with cyclosporine A
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Ofri, R., Lambrou, G. N., Allgöwer, I., Gränitz, U., Pena, T., Spiess, B. M., & Latour, E. (2009). Clinical evaluation of pimecrolimus eye drops for treatment of canine keratoconjunctivitis sicca: A comparison with cyclosporine A. The Veterinary Journal, 179, 70–77. https://doi.org/10.1016/j.tvjl.2007.08.034
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The aim of this study was to evaluate the efficacy of pimecrolimus oil-based eye drops in alleviating the clinical signs of keratoconjunctivitis sicca (KCS) in dogs and to compare the efficacy with that of cyclosporine A (CsA) ointment. An open-label, multicenter study enrolling 44 dogs previously untreated with CsA was conducted. Dogs were randomly assigned to a treatment group and medicated twice daily for 8 weeks. After that time the mean increase (±SEM) in the Schirmer tear test was 9.2 ± 1.6 mm/min in the pimecrolimus group and 5
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- Ofri, R
- Lambrou, G N
- Allgöwer, I
- Gränitz, U
- Spiess, B M
- Latour, E
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Ofri, R., Lambrou, G. N., Allgöwer, I., Gränitz, U., Pena, T., Spiess, B. M., & Latour, E. (2009). Clinical evaluation of pimecrolimus eye drops for treatment of canine keratoconjunctivitis sicca: A comparison with cyclosporine A. The Veterinary Journal, 179, 70–77. https://doi.org/10.1016/j.tvjl.2007.08.034
