Publication: The receptor kinase FER is a RALF-regulated scaffold controlling plant immune signaling
The receptor kinase FER is a RALF-regulated scaffold controlling plant immune signaling
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Stegmann, M., Monaghan, J., Smakowska-Luzan, E., Rovenich, H., Lehner, A., Holton, N., Belkhadir, Y., & Zipfel, C. (2017). The receptor kinase FER is a RALF-regulated scaffold controlling plant immune signaling. Science, 355(6322), 287–289. https://doi.org/10.1126/science.aal2541
Abstract
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Abstract
In plants, perception of invading pathogens involves cell-surface immune receptor kinases. Here, we report that the Arabidopsis SITE-1 PROTEASE (S1P) cleaves endogenous RAPID ALKALINIZATION FACTOR (RALF) propeptides to inhibit plant immunity. This inhibition is mediated by the malectin-like receptor kinase FERONIA (FER), which otherwise facilitates the ligand-induced complex formation of the immune receptor kinases EF-TU RECEPTOR (EFR) and FLAGELLIN-SENSING 2 (FLS2) with their co-receptor BRASSINOSTEROID INSENSITIVE 1-ASSOCIATED KINAS
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- Stegmann, Martin
- Monaghan, Jacqueline
- Smakowska-Luzan, Elwira
- Rovenich, Hanna
- Lehner, Anita
- Holton, Nicholas
- Belkhadir, Youssef
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Stegmann, M., Monaghan, J., Smakowska-Luzan, E., Rovenich, H., Lehner, A., Holton, N., Belkhadir, Y., & Zipfel, C. (2017). The receptor kinase FER is a RALF-regulated scaffold controlling plant immune signaling. Science, 355(6322), 287–289. https://doi.org/10.1126/science.aal2541
