Publication: Circadian Clocks, Sleep, and Metabolism
Circadian Clocks, Sleep, and Metabolism
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Nowak, N., Rawleigh, A., & Brown, S. A. (2021). Circadian Clocks, Sleep, and Metabolism. In O. Engmann & M. Brancaccio (Eds.), Circadian Clock in Brain Health and Disease (No. 1344; Issue 1344, pp. 21–42). Springer. https://doi.org/10.1007/978-3-030-81147-1_2
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A molecular circadian clock exists not only in the brain, but also in most cells of the body. Research over the past two decades has demonstrated that it directs daily rhythmicity of nearly every aspect of metabolism. It also consolidates sleep-wake behavior each day into an activity/feeding period and a sleep/fasting period. Otherwise, sleep-wake states are mostly controlled by hypothalamic and thalamic regulatory circuits in the brain that direct overall brain state. Recent evidence suggests that hypothalamic control of appetite and
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Nowak, N., Rawleigh, A., & Brown, S. A. (2021). Circadian Clocks, Sleep, and Metabolism. In O. Engmann & M. Brancaccio (Eds.), Circadian Clock in Brain Health and Disease (No. 1344; Issue 1344, pp. 21–42). Springer. https://doi.org/10.1007/978-3-030-81147-1_2