Publication: When Secretomes Meet Anthelmintics: Lessons for Therapeutic Interventions
When Secretomes Meet Anthelmintics: Lessons for Therapeutic Interventions
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Moreno, Y., Geary, T. G., & Tritten, L. (2021). When Secretomes Meet Anthelmintics: Lessons for Therapeutic Interventions. Trends in Parasitology, 37, 468–475. https://doi.org/10.1016/j.pt.2021.01.007
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Helminth secretomes comprise many potential immunomodulators. The molecular and functional diversity of these entities and their importance at the host-parasite interface have been increasingly recognized. It is now common to hypothesize that parasite-derived molecules (PDMs) are essential mediators used by parasites to establish and remain in their hosts. Suppression of PDM release has been reported for two anthelmintic drug classes, the benzimidazoles and macrocyclic lactones, the mechanisms of action of which remain incompletely re
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- Moreno, Yovany
- Geary, Timothy G
- Tritten, Lucienne
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Citations
Moreno, Y., Geary, T. G., & Tritten, L. (2021). When Secretomes Meet Anthelmintics: Lessons for Therapeutic Interventions. Trends in Parasitology, 37, 468–475. https://doi.org/10.1016/j.pt.2021.01.007
