Publication: Estimating antibiotic coverage from linked microbiological and clinical data from the Swiss Paediatric Sepsis Study to support empiric antibiotic regimen selection
Estimating antibiotic coverage from linked microbiological and clinical data from the Swiss Paediatric Sepsis Study to support empiric antibiotic regimen selection
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Cook, A., Atkinson, A., Kronenberg, A., Agyeman, P. K. A., Schlapbach, L. J., Swiss Pediatric Sepsis Study Group, Berger, C., & Bielicki, J. A. (2023). Estimating antibiotic coverage from linked microbiological and clinical data from the Swiss Paediatric Sepsis Study to support empiric antibiotic regimen selection. Frontiers in Pediatrics, 11, 1124165. https://doi.org/10.3389/fped.2023.1124165
Abstract
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Abstract
In light of rising antibiotic resistance, better methods for selection of empiric antibiotic treatment based on clinical and microbiological data are needed. Most guidelines target specific clinical infections, and variably adjust empiric antibiotic selection by certain patient characteristics. Coverage estimates reflect the probability that an antibiotic regimen will be active against the causative pathogen once confirmed and can provide an objective basis for empiric regimen selection. Coverage can be estimated for specific infectio
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Creators (Authors)
- Cook, Aislinn
- Atkinson, Andrew
- Kronenberg, Andreas
- Agyeman, Philipp K A
- Schlapbach, Luregn J
- Berger, Christoph
- Bielicki, Julia Anna
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Cook, A., Atkinson, A., Kronenberg, A., Agyeman, P. K. A., Schlapbach, L. J., Swiss Pediatric Sepsis Study Group, Berger, C., & Bielicki, J. A. (2023). Estimating antibiotic coverage from linked microbiological and clinical data from the Swiss Paediatric Sepsis Study to support empiric antibiotic regimen selection. Frontiers in Pediatrics, 11, 1124165. https://doi.org/10.3389/fped.2023.1124165
