Publication: Decellularized homologous tissue-engineered heart valves as off-the-shelf alternatives to xeno- and homografts
Decellularized homologous tissue-engineered heart valves as off-the-shelf alternatives to xeno- and homografts
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Dijkman, P. E., Driessen-Mol, A., Frese, L., Hoerstrup, S. P., & Baaijens, F. P. T. (2012). Decellularized homologous tissue-engineered heart valves as off-the-shelf alternatives to xeno- and homografts. Biomaterials, 33(18), 4545–4554. https://doi.org/10.1016/j.biomaterials.2012.03.015
Abstract
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Decellularized xenogenic or allogenic heart valves have been used as starter matrix for tissue-engineering of valve replacements with (pre-)clinical promising results. However, xenografts are associated with the risk of immunogenic reactions or disease transmission and availability of homografts is limited. Alternatively, biodegradable synthetic materials have been used to successfully create tissue-engineered heart valves (TEHV). However, such TEHV are associated with substantial technological and logistical complexity and have not y
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- Dijkman, Petra E
- Driessen-Mol, Anita
- Frese, Laura
- Hoerstrup, Simon P
- Baaijens, Frank P T
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Dijkman, P. E., Driessen-Mol, A., Frese, L., Hoerstrup, S. P., & Baaijens, F. P. T. (2012). Decellularized homologous tissue-engineered heart valves as off-the-shelf alternatives to xeno- and homografts. Biomaterials, 33(18), 4545–4554. https://doi.org/10.1016/j.biomaterials.2012.03.015
