Publication: Intraoperative engineering of osteogenic grafts combining freshly harvested, human adipose-derived cells and physiological doses of bone morphogenetic protein-2
Intraoperative engineering of osteogenic grafts combining freshly harvested, human adipose-derived cells and physiological doses of bone morphogenetic protein-2
Date
Date
Date
Citations
Mehrkens, A., Saxer, F., Güven, S., Hoffmann, W., Müller, A. M., Jakob, M., Weber, F. E., Martin, I., & Scherberich, A. (2012). Intraoperative engineering of osteogenic grafts combining freshly harvested, human adipose-derived cells and physiological doses of bone morphogenetic protein-2. European Cells and Materials (ECM), 24, 308–319. https://doi.org/10.22203/eCM.v024a22
Abstract
Abstract
Abstract
Engineered osteogenic constructs for bone repair typically involve complex and costly processes for cell expansion. Adipose tissue includes mesenchymal precursors in large amounts, in principle allowing for an intraoperative production of osteogenic grafts and their immediate implantation. However, stromal vascular fraction (SVF) cells from adipose tissue were reported to require a molecular trigger to differentiate into functional osteoblasts. The present study tested whether physiological doses of recombinant human BMP-2 (rhBMP-2) c
Metrics
Downloads
Views
Additional indexing
Creators (Authors)
- Mehrkens, Arne
- Saxer, Franziska
- Güven, Sinan
- Hoffmann, Waldemar
- Müller, Andreas M
- Jakob, Marcel
- Weber, Franz E
- Martin, Ivan
- Scherberich, Arnaud
Volume
Volume
Volume
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Free Access at
Free Access at
Free Access at
Publisher DOI
Metrics
Downloads
Views
Citations
Mehrkens, A., Saxer, F., Güven, S., Hoffmann, W., Müller, A. M., Jakob, M., Weber, F. E., Martin, I., & Scherberich, A. (2012). Intraoperative engineering of osteogenic grafts combining freshly harvested, human adipose-derived cells and physiological doses of bone morphogenetic protein-2. European Cells and Materials (ECM), 24, 308–319. https://doi.org/10.22203/eCM.v024a22
